Set more than a decade after the events of the first film, learn the story of the Sully family (Jake, Neytiri, and their kids), the trouble that follows them, the lengths they go to keep each other safe, the battles they fight to stay alive, and the tragedies they endure.
After Megamind, a highly intelligent alien supervillain, defeats his long-time nemesis Metro Man, Megamind creates a new hero to fight, but must act to save the city when his "creation" becomes an even worse villain than he was.