Professor Ren Xinzheng resigns to start a mentoring class for traditional Chinese medicine, hoping to train true successors. His students—Sun Toutou, his son Ren Tianzhen, lawyer-turned-student Yang Xiaohong, pediatrician Peng Shiyan, and aspiring doctor Zhao Liquan—struggle to get along, but must work through their differences to preserve the legacy of Chinese medicine.
Ruan Liuzheng returns to her hometown after seven years, and becomes a neurosurgeon at Beiya Hospital. However, she didn't expect to meet her ex-husband, Ning Zhiqian, who is the most experienced neurosurgeon. Ruan Liuzheng is no longer the weak and timid girl, and she shows resolute and determination in both her work and relationship. When they were in Africa to execute medical relief efforts, Ning Zhiqian was injured in a gunshot. Ruan Liuzheng didn't leave his side, and fought hard to save him from the brink of death. The two have gained a new understanding of life, and begun a new relationship again.
In 2008, Xiao Feng is a downcast e-sports team leader who is barely keeping his team together. E-sports is in its infancy and there is little money to be earned. Xiao Feng's team is looked down upon and ridiculed, yet they insist on fighting for their dreams. In 2019, Lu Xiao Bei is a genius in the same game, a masterful player. In reality, he is a disabled young man in a wheelchair. He vowed to continue his brother's legacy to become a professional e-sports player who died in an accident before he can turn pro. Despite living 11 years apart, a cosmic glitch allowed the two to communicate first by voice chat then meeting up in-game. This formed the basis of their friendship which transcend time and ultimately saved Xiao Feng's life in 2008. This allowed the two to meet face to face in the present. They then join forces and form their own team to achieve their ultimate goal of winning the championship.
The film tells the story of the early Ming Dynasty, the reappearance of the Yin soldiers, the brocade guards Xu Li (Lin Fengsong) was assigned by the Prince to go to the Cold Mountain Temple to check out the Yin Tiger talisman visions, the search for the truth in the process of getting acquainted with the Jalan girl Yutum (Liao Huijia), the abbot of the Cold Mountain Temple Xiangxin, and hand in hand with the East Japan demon god Rintaro forces