On the occasion of the birthday feast of Queen Wu Zetian, it was suddenly reported that the "red-eyed monster" was committing a chaotic case, and Wu Zetian ordered Di Renjie to supervise the case. Di Renjie and his apprentice Chen Jiangqiao came to Fangzhou to investigate the case, and chanced upon Shen Qingqing, who was also investigating the case. Through the investigation of the case, the trio gradually approached the truth behind the "red-eyed monster", which led to a series of serial incidents. In the process of dealing with this series of incidents, Di Renjie was upright, putting the common people of Li people first, and expressing a sense of responsibility and mission that "everyone is responsible for the rise and fall of the world", and finally successfully solved the mystery.
On her wedding day, Chu Jiuling discovers her uncle, the Emperor, killed her father. Betrayed and nearly assassinated by her husband, she is rescued by a physician and takes on a new identity as Jun Jiuling. Using her medical skills and wit, she aids a noble family, infiltrates the capital, and uncovers political corruption while winning the people’s trust.
Renhe Hospital nurse Zhang Shumei is forced to resign after being suspected of accidentally killing a patient. Zhang Shumei’s 4 year old daughter is abducted, and she herself dies in a car accident a couple of years later. 30 years later, Zhang Shumei’s son Zhuang Shu returns to the hospital as a surgeon who is intent on unraveling the secret behind his family’s misfortune.
