This dark medical drama examines the meaning of human life, centring on a team of unidentified black-market doctors who undertake any kind of surgery with superhuman surgical skills and exorbitant medical expenses. Hazama Eisuke, also known as "Ace", is a genius surgeon who works as a patissier during the day. He has an operating room equipped with the latest equipment in the basement of his patisserie, where he performs surgeries on patients who have been abandoned by others. Shimoyamada Jo, also known as "Joker", is a brilliant international lawyer and a negotiator with patients.
Haruno Shotaro and his girlfriend Mimori Arisa get into a car accident. The next moment, when he wakes up, he finds out that he is in the hospital and has a cast on his right foot and left hand. Soon, Haruno Shotaro thinks that something is really strange with the hospital. The hospital has weird patients and the doctors and nurses seem to be hiding something. A mysterious serial murder case also takes place outside the hospital. What is the connection between the hospital and the serial murder case? What is happening in the hospital?
Nagisa Mio, an oceanographer at Shibaura University of Marine Science and Technology, is very interested in fishes and loves the sea. Despite her cheerful smile and kind, good-natured personality, she is reticent about her family and past. Hasuda Rintaro, the second son of a wealthy family, is feared by the people around him as he comes across as someone who is hard to approach. But beneath that armour is a young man with a pure heart and no airs. He has returned to Japan due to his father’s poor health and is put in charge of a marine resort development project. While Mio wants to protect the ocean and opposes the resort’s development, Rintaro is staking his life on it. These two people who seem as if they live in different worlds, meet each other over the project and eventually fall in love. However, theirs is a forbidden romance because Mio has a secret that will shock everyone.
The story continues from the Japanese SIGNAL drama series. In 2021, a limousine taxi driver causes an accident on a highway, and a high-level government official dies in the accident. The cold case investigation unit, including Kento Saegusa and team leader Misaki Sakurai, have doubts about the case. Meanwhile, in 2009, administrative officers die consecutively in car accidents. The police announce these deaths as accidents. Takeshi Ōyama believes that these deaths were not the product of simple accidents. At 11:23 pm, a walkie-talkie turns on and makes a connection between the future and past. Kento Saegusa and Takeshi Ōyama face the threat of bioterrorism.
While helping his family for packing, Takuto found a pair of mysterious opera glasses from a piled-up cardboard box which turns out to be his grandma’s relic. The magical opera glasses named ‘Gyoro’ suddenly came to life when Takuto touched it. Gyoro brings back happy memories to grandpa and mom of going to theaters with grandma. With Gyoro, Takuto gradually becomes fascinated by the world of theater.
When Mio was young, she lost her parents in a great flood and also became separated from her best friend Noe. Afterwards, Mio found her talent in cooking and eventually became a cook. Meanwhile, Noe has become an oiran (high-ranking courtesan).
Featuring the boys of Johnny's West, a gang of zany transfer students are recruited for a mysterious mission ordained by their shadowy principal.
Aino Hingo used to work as an associate professor of ethnology. He now works as the director of a matchmaking agency. His assistant is Sister Elizabeth. The high entrance fee at the matchmaking agency is two million yen, but the matchmaking agency has a 100% success rating for their clients getting married. They match customers based on the client's conditions. The secret behind their 100% marriage rate is Shingo Aino's counseling, relying on his knowledge in ethology.
Takeshi Kaga, real name Shigekatsu Katsuta, is a well-known stage and movie actor in Japan who is best known internationally for his portrayal of Chairman Kaga in the Japanese television show Iron Chef produced by Fuji TV.
