Carolina has a perfect life: she lives in a luxurious house, works in a fashion magazine and is married to a successful publicist. One day everything goes to waste: she discovers that she is sterile, the same day that her husband leaves her for her best friend, who, in addition, is pregnant with him. After the impact of this news, Carolina has a crisis, drinks too much, trips and falls from the second floor of her house, a fact that is interpreted as a suicide attempt.Carolina is interned against her will, in the exclusive psychiatric center Eden. In that place she will meet a group of "madmen" who will help her heal and glimpse that her previous life was not so perfect. He also discovers that perhaps the craziest are those outside the psychiatric hospital.
Trini's daughter is sad that her best friend is leaving Saint Michael School since her mother can't keep paying for it. Trini promises her daughter that this won't happen and decides to put together a plan with the other "mamis" of the group to solve the problem. But this mission will be much more difficult than they thought and they will have to stick together as a group.
The relationship between Ricky and his daughter will suffer when the girl's mother returns and wants her back.
Beatriz married Vicente, her ideal man. The problem is that it was not only ideal for her, but for everyone else. Vicente dies in "a night of passion" from a heart attack, Beatriz's uncontrollable jealousy leads her to hires Dante, a poker player who will seduce the five suspects and by doing so, shed light on to the mystery.