Determined to ensure Superman's ultimate sacrifice was not in vain, Bruce Wayne aligns forces with Diana Prince with plans to recruit a team of metahumans to protect the world from an approaching threat of catastrophic proportions.
Sometime in the near future, paraplegic prison inmate Matt Mills meets "The Board" of Satoshi-Telefair Industries, who thank him for joining the Program. Under pressure and with a promise to make him walk again, Mills agrees to volunteer. He is injected with a synthetic nanomaterial and suffocated, only to wake up with restored use of his legs, yet alone in a steel cell in the first spoke of an experimental apparatus - The Wheel. A series of assailants inflict a multitude of damage to Mills' body and torment his mind, yet the synthetic nanomaterial not only restores his damaged organs, it re-engineers his strength. The experiment might be designed to kill, but Mills is determined to survive - and get back to his daughter before The Board finds her first.
In 1962 England, a young couple finds their idyllic romance colliding with issues of sexual freedom and societal pressure, leading to an awkward and fateful wedding night.
Fuelled by his restored faith in humanity and inspired by Superman's selfless act, Bruce Wayne and Diana Prince assemble a team of metahumans consisting of Barry Allen, Arthur Curry and Victor Stone to face the catastrophic threat of Steppenwolf and the Parademons who are on the hunt for three Mother Boxes on Earth.